Вестник МГТУ, 2023, Т. 26, № 3.

Мерзлякова Н. В. и др. Прогнозирование антимикробной активности пищевого пептида. Mehta, K., Sharma, P., Mujawar, S., Vyas, A. 2022. Role o f antimicrobial peptides in treatment and prevention of mycobacterium tuberculosis: A review. International Journal o f Peptide Research and Therapeutics, 28(5). Article number: 132. DOI: https://doi.org/10.1007/s10989-022-10435-9. Mink, C., Strandberg, E., Wadhwani, P., Melo, M. N. et al. 2021. Overlapping properties o f the short membrane- active peptide BP100 with (i) polycationic TAT and (ii) a-helical magainin family peptides. Frontiers in Cellular and Infection Microbiology, 11. Article number: 609542. DOI: https://doi.org/10.3389/ fcimb.2021.609542. Mishra, A. K., Choi, J., Moon, E., Baek, K.-H. 2018. Tryptophan-rich and proline-rich antimicrobial peptides. Molecules, 23(4). Article number: 815. DOI: https://doi.org/10.3390/molecules23040815. Moretta, A., Scieuzo, C., Petrone, A. M., Salvia, R. et al. 2021. Antimicrobial peptides: A new hope in biomedical and pharmaceutical fields. Frontiers in Cellular and Infection Microbiology , 11. Article number: 668632. DOI: https://doi.org/10.3389/fcimb.2021.668632. Peng, S.-Y., You, R.-I., Lai, M.-J., Lin, N.-T. et al. 2017. Highly potent antimicrobial modified peptides derived from the Acinetobacter baumannii phage endolysin LysAB2. Scientific Reports, 7. Article number: 11477. DOI: https://doi.org/10.1038/s41598-017-11832-7. Picariello, G., Iacomino, G., Mamone, G., Ferranti, P. et al. 2013. Transport across Caco-2 monolayers of peptides arising from in vitro digestion o f bovine milk proteins. Food Chemistry, 139(1-4), pp. 203-212. DOI: https://doi.org/10.1016/j.foodchem.2013.01.063. Pino-Angeles, A., Leveritt, III J. M., Lazaridis, T. 2016. Pore structure and synergy in antimicrobial peptides of the magainin family. PLOS Computational Biology, 12(1). Article number: e1004570. DOI: https://doi.org/ 10.1371/journal.pcbi.1004570. Porto, W. F., Irazazabal, L., Alves, E. S. F., Ribeiro, S. M. 2018. In silico optimization o f a guava antimicrobial peptide enables combinatorial exploration for peptide design. Nature Communications, 9(1). Article number: 1490. DOI: https://doi.org/10.1038/s41467-018-03746-3. Silva, T., Gomes, M. S. 2017. Immuno-stimulatory peptides as a potential adjunct therapy against intra- macrophagic pathogens. Molecules, 22(8). Article number: 1297. DOI: https://doi.org/10.3390/molecules22081297. Stelwagen, K., Carpenter, E., Haigh, B., Hodgkinson, A. et al. 2009. Immune components of bovine colostrum and milk. Journal o fAnimal Science, 87(suppl_13), pp. 3-9. DOI: https://doi.org/10.2527/jas.2008-1377. Travis, S. M., Anderson, N. N., Forsyth, W. R., Espiritu, C. 2000. Bactericidal activity of mammalian cathelicidin- derived peptides. Infection and Immunity, 68(5), pp. 2748-2755. DOI: https://doi.org/10.1128/iai.68.5.2748- 2755.2000. Tucs, A., Tran, D. P., Yumoto, A., Ito, Y. et al. 2020. Generating ampicillin-level antimicrobial peptides with activity-aware generative adversarial networks. ACS Omega, 5(36), pp. 22847-22851. DOI: https://doi.org/ 10.1021/acsomega.0c02088. Yan, J., Cai, J., Zhang, B., Wang, Y. et al. 2022. Recent progress in the discovery and design o f antimicrobial peptides using traditional machine learning and deep learning. Antibiotics, 11(10). Article number: 1451. DOI: https://doi.org/10.3390/antibiotics11101451. Yang, M., Tan, M., Wu, J., Chen, Z. et al. 2019. Prevalence, characteristics, and outcome of cow’s milk protein allergy in Chinese infants: A population-based survey. Journal o f Parenteral and Enteral Nutrition, 43(6), pp. 803-808. DOI: https://doi.org/10.1002/jpen.1472. Zhang, S., Ma, M., Shao, Z., Zhang, J. et al. 2021. Structure and formation mechanism of antimicrobial peptides temporin B- and L-induced tubular membrane protrusion. International Journal o f Molecular Sciences, 22(20). Article number: 11015. DOI: https://doi.org/10.3390/ijms222011015. Сведения об авторах Мерзлякова Наталия Вадимовна - ул. Карла Либкнехта, 42, г. Екатеринбург, Россия, 620075; Уральский государственный аграрный университет, аспирант; e-mail : merzlyakova@xk3.ru Natalya V. Merzlyakova - 42 Karl Liebknecht Str., Yekaterinburg, Russia, 620075; Ural State Agrarian University, PhD Student; e-mail : merzlyakova@xk3.ru Тихонов Сергей Леонидович - ул. Карла Либкнехта, 42, г. Екатеринбург, Россия, 620075; Уральский государственный аграрный университет, д-р техн. наук, профессор; e-mail: tihonov75@bk.ru, ORCID : https://orcid.org/0000-0003-4863-9834 Sergey L. Tikhonov - 42 Karl Liebknecht Str., Yekaterinburg, Russia, 620075; Ural State Agrarian University, Dr Sci. (Engineering), Professor; e-mail: tihonov75@bk.ru, ORCID : https://orcid.org/0000-0003-4863-9834 240