Sandimirov S. Screening studies of POP levels in fish from selected lakes in the Paz watercourse / In State of the environment in the Norwegian, Finnish and Russian border area. The Finnish Environment. Finland, Jyvaskyla: Kopijyva Oy. 2007, №6.

Screening studies o f POPs in fish from the Paz watercourse Kuetsijarvi, pike 0,6 0,5 I 0,4 ! о 0,3 E> n 0,2 <u 0,1 0 516 517 519 409 431 Males Females Fish numbers Figure 13. Cytochrome P-450 aniline hydroxylase activity in pike microsomes (Kuetsjarvi). Cytochrome P-450 activity were higher in pike (females and males) from Lake Kuetsjarvi, which had the highest contaminant levels, compared to males and females from Rajakoski. This indicate an activation of a protective detoxification mechanism by the monooxygenase system, which can reduce unfavourable effects on fish. 6.2. Bile acids in fish bile The data on bile acids are presented as cholate index-relation between cholic acid content (mg/ml) and total quantity of bile acids (mg/ml) in bile per cent (ChI%). The analytical results showed that male bile acid profiles varied a lot. Male and female pike had a lower Cholate Index (ChI%) than whitefish (see Figure 14 and Figure 15). Bile from male whitefish from the most contaminated area was characterized by lower level of ChI% than bile from male whitefish from the area with lowest contamination levels (Figure 15 and Figure 16). Figure 14. Bile acids content in pike bile (Rajakoski) Akvaplan-niva report APN 514-3365.02 24

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